Endocrine Abstracts

The oxytocin (OT) treatment protects heart against ischemia. Here we investigated heart-derived H9c2 cells in simulated ischemia-reperfusion (I-R) experiments in order to examine the mechanism of OT-induced cardioprotection.Results: I-R was induced in an anoxic chamber for 2 h and followed by 2 h of reperfusion. In comparison to normoxia, I-R resulted in decrease of formazan production by H9c2 cells to 63.5±1.7% (MTT assay) and enhanced apoptosis fr...